Fisetin, a chemical found in vegetables and fruits, has been studied by researchers at the Salk Institute for decades. It has been proven to help improve memory. The researchers developed a synthetic version of fisetin called CMS121. They tested this on a type of mouse that develops an Alzheimer-like disease and they established that CMS121 produced differences in lipid peroxidation, which is responsible for brain cell damage associated with Alzheimer’s disease.
This study published in Redox Biology confirmed that Alzheimer’s disease lowers lipid peroxidation and that this promising new drug can normalize those changes and reverse memory loss associated with Alzheimer’s.
In the US, Alzheimer’s is the 6th leading cause of death and it’s the most common type of dementia. Over 5 million Americans have Alzheimer’s disease. The biggest risk factor for Alzheimer’s is old age. It usually appears in adults in their mid-60s.